ApoE Gene Test

Methylenetetrahydrofolate Reductase (MTHFR) At-Home Test Kit


Our ApoE Gene Mutation Test Kit looks for the presence of the APOE4 variant, which is associated with increased risk of late-onset Alzheimer’s disease.

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What is ApoE, Apo-E, Apolipoprotein E?

The APOE gene makes a lipoprotein that is responsible for packaging cholesterol and other fats.  There are 3 alleles of the ApoE gene (E2, E3, E4) with E3 being most common in the US population. The other alleles or versions are associated with a number of health conditions related to ageing and cardiovascular disease

Conditions Associated with ApoE

  • Alzheimer Disease - APOE specifically carrying the E4 allele increases the risk for developing late-onset Alzheimer disease in people over 65. The risk is dependent on the number of copies of E4. An individual with 1 copy has a lifetime risk as high as 20% while having 2 copies of E4 can increase risk up to 50% However, the E2 variant can be protective.
  • Macular Degeneration - is a eye disease that results in vision loss usually in older adults.
  • Dementia with Lewy Bodies - The E4 variant can increase the risk of developing this type of dementia.

Sample Type

  • At-Home Test kit with a buccal swab collected with Zymo SafeCollect Swab

Why should I get tested?

  • If you have a strong family history of Alzheimer Disease or Dementia in the family
  • If you are developing signs of Dementia, Memory Loss, Alzheimer Disease or Macular Degeneration at an earlier than expected age
  • If you are starting to get forgetful, have confusion, or losing time
  • If there is age related impact on judgement
  • If there is any sign of progressive dementia

Turnaround time

  • Note: Result turnaround times are only an estimate and may be subject to change.
  • Test turnaround time for an electrolyte panel is typically 1-2 business days.

Patient Preparation

  • No special preparation is needed


  • These tests are meant for individual consumption. If you wish to order multiple test kits for multiple people, you will need to register as a provider.
  • How do I register as a provider?

Additional information

Weight 1 lbs
Dimensions 10 × 6 × 1.25 in

Self-Test Collection Instructions

Please download the PDF below for sample collection instructions.

Buccal Swab PDF


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