ApoE Gene Mutation Test Kit

What is ApoE, Apo-E, Apolipoprotein E?

The APOE gene makes a lipoprotein that is responsible for packaging cholesterol and other fats.  There are 3 alleles of the ApoE gene (E2, E3, E4) with E3 being most common in the US population. The other alleles or versions are associated with a number of health conditions related to ageing and cardiovascular disease

Conditions Associated with ApoE

• Alzheimer Disease - APOE specifically carrying the E4 allele increases the risk for developing late-onset Alzheimer disease in people over 65. The risk is dependent on the number of copies of E4. An individual with 1 copy has a lifetime risk as high as 20% while having 2 copies of E4 can increase risk up to 50% However, the E2 variant can be protective.
• Macular Degeneration - is a eye disease that results in vision loss usually in older adults.
• Dementia with Lewy Bodies - The E4 variant can increase the risk of developing this type of dementia.

Sample Type

• At-Home Test kit with a buccal swab collected with Zymo SafeCollect Swab

Why should I get tested?

• If you have a strong family history of Alzheimer Disease or Dementia in the family
• If you are developing signs of Dementia, Memory Loss, Alzheimer Disease or Macular Degeneration at an earlier than expected age
• If you are starting to get forgetful, have confusion, or losing time
• If there is age related impact on judgement
• If there is any sign of progressive dementia

Shipping

• Note: Result turnaround times are only an estimate and may be subject to change.
  • Choose the option that is right for you.
  • Depending on what you choose shipments can arrive anywhere from 1-5 days

Patient Preparation

• No special preparation is needed

Disclaimer

• These tests are meant for individual consumption. If you wish to order multiple test kits for multiple people, you will need to register as a provider.
• How do I register as a provider?
  • Fill out our New Client Form
  • Or contact us via phone or email