Comprehensive APOE Testing: Uncover Your Genetic Risk for Alzheimer’s and Heart Disease

$149.00

Unlock the secrets of your genetic makeup with our APOE Test Kit, right from the comfort of your home. This user-friendly kit provides crucial information about your genetic risk for Alzheimer’s and heart disease, empowering you with the knowledge you need for informed health decisions and proactive lifestyle choice. Our ApoE Gene Mutation Test Kit looks for the presence of the APOE4 variant, which is associated with increased risk of late-onset Alzheimer’s disease.

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What is ApoE, Apo-E, Apolipoprotein E?

The APOE gene makes a lipoprotein that is responsible for packaging cholesterol and other fats.  There are 3 alleles of the ApoE gene (E2, E3, E4) with E3 being most common in the US population. The other alleles or versions are associated with a number of health conditions related to ageing and cardiovascular disease

Conditions Associated with ApoE

  • Alzheimer’s Disease Susceptibility: Strongly linked with APOE variants, especially APOE4, this condition is a primary focus in genetic risk assessment.
  • Cardiovascular Diseases: APOE genotypes are associated with differing risks and severities of heart conditions, including heart attacks and strokes.
  • Hyperlipidemia: Certain APOE alleles can influence lipid levels, increasing the risk of elevated cholesterol and triglycerides.
  • Type 2 Diabetes Risk: Research indicates a connection between APOE genotypes and the risk of developing type 2 diabetes.
  • Cerebral Amyloid Angiopathy: APOE variants, particularly APOE4, are linked to this condition, characterized by amyloid deposits in cerebral blood vessels.
  • Dementia Risk: Beyond Alzheimer’s, APOE genotypes can influence the risk and progression of various forms of dementia.
  • Neurological Disorders: Certain APOE alleles may impact the susceptibility to or severity of other neurological conditions.
  • Atherosclerosis: APOE genotypes can affect the development of atherosclerosis, contributing to plaque buildup in arteries.
  • Age-Related Cognitive Decline: APOE variants, especially APOE4, are associated with varying rates of cognitive decline in the aging population.
  • Liver Disease: APOE genotypes can influence liver function and susceptibility to liver disorders.

Sample Type

  • At-Home Test kit with a buccal swab collected with Zymo SafeCollect Swab

Why Should I Get Tested for ApoE

  • Family History of Alzheimer’s Disease: If Alzheimer’s runs in your family, an APOE test can provide insights into your genetic risk.
  • Personalized Health Strategies: Understanding your APOE genotype can guide tailored lifestyle and health choices for better brain health.
  • Risk Assessment for Heart Disease: Since APOE is linked to cardiovascular health, testing can be crucial for heart disease prevention strategies.
  • Informed Medical Decision-Making: Knowledge of your APOE status aids healthcare providers in developing more effective, personalized treatment plans.
  • Early Intervention Opportunities: Identifying a higher genetic risk can lead to early interventions that may slow down or prevent disease progression.
  • Managing Cholesterol Levels: APOE genotyping can offer insights into your body’s lipid metabolism, helping in managing cholesterol levels.
  • Cognitive Health Monitoring: For those experiencing memory issues or cognitive decline, APOE testing can be a step in understanding the underlying causes.
  • Research Participation: Knowing your APOE status can qualify you for certain medical research studies or clinical trials.
  • Proactive Health Planning: For individuals seeking a proactive approach to their health, APOE testing provides valuable genetic information.
  • Peace of Mind: Understanding your genetic makeup can offer peace of mind or prepare you for potential health challenges in the future.

FAQs about the ApoE Test Kit

Is the APOE genotype test appropriate for children?
No, the APOE genotype test is not appropriate for children. It is specifically designed to detect the presence of the APOE4 variant, which is associated with late-onset Alzheimer’s disease. Since Alzheimer’s disease typically affects individuals over the age of 60-65, the test is not relevant or informative for children.

How can the APOE genotype results help identify individuals at a higher risk for developing late-onset Alzheimer’s disease?
The APOE genotype results can help identify individuals who are at a higher risk for developing late-onset Alzheimer’s disease. The presence of the APOE4 variant is associated with an increased risk of developing late-onset Alzheimer’s disease, and by detecting this variant, individuals can be informed about their higher risk and take appropriate measures for early intervention or monitoring.

How can the APOE genotype results provide supplementary information for the clinical diagnosis of Alzheimer’s disease?
The APOE genotype results can provide supplementary information for the clinical diagnosis of Alzheimer’s disease in patients with dementia. By identifying the presence of the APOE4 variant, healthcare professionals can better assess a patient’s risk for developing late-onset Alzheimer’s disease.

What does the APOE4 variant indicate?
The presence of the APOE4 variant indicates an increased risk of late-onset Alzheimer’s disease (AD).

What is the purpose of the APOE genotype results?
The purpose of the APOE genotype results is to detect the presence of the APOE4 variant, which is associated with an increased risk of late-onset Alzheimer’s disease (AD).

 

Turnaround time

  • Note: Result turnaround times are only an estimate and may be subject to change.
  • Test turnaround time for an electrolyte panel is typically 1-2 business days.

Patient Preparation

  • No special preparation is needed
Weight 1 lbs
Dimensions 10 × 6 × 1.25 in

Self-Test Collection Instructions

Please download the PDF below for sample collection instructions.

Buccal Swab PDF

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Appointments

Locally in Central Florida:

Go to Patient Portal Page   1. Create Account. 2. Go to New Order and Schedule

Applied InGENuity Diagnostics Laboratory. Located at 7040 Lake Ellenor Dr, Orlando, FL 32809
Applied InGENuity Diagnostics Laboratory. Located at 7040 Lake Ellenor Dr, Orlando, FL 32809

 

NOT LOCAL

  1. Please wait 24 hours for us to place your order
  2. Go to any Quest Patient Service Center

 

 

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