Familial Alzheimer Test Kit


The purpose of this Familial Alzheimer Test Kit is to identify pathogenic variants in the amyloid protein precursor (APP), (PSEN1), and (PSEN2) genes.

What is Familial Alzheimer or Early Onset Alzheimer?

Familial or Early Onset Alzheimer is essentially Alzheimer’s disease that is characterized by cognitive or memory issues that impact functioning due to neurodegeneration. In Early-Onset or Familial forms of this disorder, brain functioning is impaired at an earlier age than traditional age-associated dementia. Patients experience memory issues, cognitive decline, or behavior changes between the ages of 30-60. In some patients, ataxia and motor functioning may also be impaired. Alzheimer’s disease is due to the development of brain atrophy and/or the development of plaques in various parts of the brain.

Genes Associated with Early-Onset Alzheimer Disease

  • APOE – This gene is associated with increased risk of dementia or Alzheimer but is not causal. We include it in the panel as it may impact clinical decision making if additional genetic alterations in other genes are identified.
  • PSEN1
  • PSEN2
  • APP

Sample Type

  • At-Home Test kit with a buccal swab collected with Zymo SafeCollect Swab

  • Blood Sample collected with Tasso Kit

Why should I get tested?

  • If you have a strong family history of Alzheimer Disease or Dementia in the family
  • If you are developing signs of Dementia, Memory Loss, Alzheimer Disease or Macular Degeneration at an earlier than expected age
  • If you are starting to get forgetful, have confusion, or losing time
  • If there is age related impact on judgement
  • If there is any sign of progressive dementia


  • Note: Result turnaround times are only an estimate and may be subject to change.
    • Choose the option that is right for you.
    • Depending on what you choose shipments can arrive anywhere from 1-5 days

Patient Preparation

  • No special preparation is needed

Insurance Billing

Insurance may be billed for this test. However, it requires a consultation and an order from a provider.  To learn more


  • These tests are meant for individual consumption. If you wish to order multiple test kits for multiple people, you will need to register as a provider.
  • How do I register as a provider?
Weight 1 lbs
Dimensions 10 × 6 × 1.25 in

Self-Test Collection Instructions

Please download the PDF below for sample collection instructions.

Buccal Swab PDF


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